I am a shortcut freak, if I can cut down the number of key strokes or amount I have to move and click my mouse I will. You can create all kinds of shortcuts using SHIFT, CTRL and the ALT keys by going thru CUI. But I found this cumbersome trying to get all the keys pressed at the same time, etc. Then I was shown the acad.pgp file and I could create all kinds of hot keys on the left side of my keyboard (I am right-handed). This is a completely editable text file were one can create 1, 2, 3 (or more) letter/number combination hot keys.
It can be accessed from the Ribbon (I am using AutoCAD Architecture 2011, but it's also on 2010 and existed back to Architectural Desktop 2004 when I first started using it. A pgp file also exists for AutoCAD LT and AutoCAD).
Go to the Mangage tab, Customize panel then to "Edit PGP". Work out what the command is, figure out a couple of hot keys and add it to the list along with the command line command in the same format at the rest.
There is a boatload of existing hotkeys already and they are in alphabetical order, so there may be one for you command already.
Save the file, go back to your drawing, re-initalize (REINIT on the command line and check the PGP File box and then OK) or close and re-open CAD and you're ready to use your new shortcut.
If a command line command exists, you can make a shortcut.
And if you upgrade your software, the pgp file does migrate with the rest of your settings!
Custom Mill Shop Drawings In-charge