I think this is a no, but is it possible to tell from within a family document which reference planes are origin defining? I'm looking to tell if one family swapped for another will 'jump'.
For instance if a door is in the project and it's origin has been somehow moved to the 'Left' reference plane and another is loaded to replace it that is defined based on 'Center Left/RIght' it will move the location of the object significantly. Is there a way to determine programatically if this will happen?