I've developed a fairly complete list of shortcuts over time (attached) with some mods to the Out Of The Box shortcuts, especially ones that get used all the time:
MM is Move (rather than Mirror)
MI is Mirror
AA is Align
TT is Text
Q is Properties
` is View Properties (to the left of the 1 key)
IO is Isolate Object (instead of HI)
CI is Category Invisible (instead of VH)
OI is Other Categories Invisible (instead of VI)
RT is Rotate
LL is Model Lines (rather than add Level)
DD is Drafting Lines
SW is Split Walls and Lines
OO is Offset
DE is Dimension (rather than Delete -- you can just hit the Delete key anyway)
etc.
I've tried to keep shortcuts close together or similar to the command name -- Isolate Object, Wall Join, Cut Geometry, etc. We have some Microsoft split keyboard lovers in our office and I'm wondering if people have developed shortcuts to deal with that.
It's one of the only things you can customize in Revit, and there's time to be saved in it, for sure.