I had to do the same action that ramon took to fix the problem, I think it'd be great if Logitech made an "AutoCAD" mouse, I think they have some really good products, but you end up having to sacrifice some of the features that you may have purchased the mouse for. I personally use the Logitech cordless MX Laser which has some really cool features but I found that I had to uninstall the mouse software "SetPoint" in order to be efficient with AutoCAD. Oh well, sometimes you have to do what you have to do, right?