Has anyone come across the following View Reference oddity?

A view is placed on a sheet, back references to the correct view.
Perform a Save to Central and all of the back reference information is lost.
Click on the viewport and it comes back, save to central and it goes again....????

Very puzzling - can't find any information regarding this type of error through Autodesk channels, may put in a support request but thought I'd ask here first.